Computer simulation of a MIP-receptor binding site (MIP = Molecularly Imprinted Polymer). Image by Ian A. Nicholls and Jesper G. Karlsson of the University of Kalmar.

A rapidly developing field that takes advantage of nanoscale templating is known as Molecular Imprinting. The concept behind the technique is to mold a material (with the desired chemical properties) around individual molecules. Upon removal of the molecular templates, one is left with regions in the molded material that fit the shape of the template molecules. It is well known from biology and chemistry that molecules tend to stick to receptors or surfaces that fit the molecular contours like a key fits a lock. Thus, molecular imprinting results in materials that can selectively bind to molecules of interest. This property is resulting in applications ranging from chemical separation to biosensors. Recently I had the opportunity to question Keith Brain and Chris Allender, organizers of the First International Workshop on Molecular Imprinting (MIP2000) at Cardiff University, UK.

Why does this technology seem to be growing so rapidly in recent times?